
Pyridoxine (Vitamin B6)
Preparation:
50 mg/ 1 mL (vial)
250 mg/1 mL (vial) SAS
Indication:
Isoniazid toxicity
Toxicity from other hydrazines (industrial hydrazines or gyromitrin-containing mushrooms)
Quantity required for 70 kg adult / 24 hours
administer an equivalent dose of pyridoxine to match the reported ingested dose of isoniazid
to a maximum of 5 grams in adults (5 grams = 20 of the 250 mg/5 mL vials) or 70 mg/kg (children)
Additional Information
Discuss with clinical toxicologist or Victorian Poison Information Centre ( 13 11 26)
Australian Injectable Drugs Handbook
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